MACHEREY-NAGEL (NUCLEODUR)

Macherey-Nagel leads HPLC innovation through advanced silica chemistry. Nucleodur C18 Gravity offers optimized surface area for excellent general-purpose separations. Pyramid concept optimizes peak shape. C8 provides alternative retention. PFP delivers unique aromatic selectivity for fluorinated pharmaceuticals. NH2 addresses carbohydrate analysis. HILIC provides dedicated hydrophilic selectivity. Polar-RP introduces intermediate selectivity. Phenyl provides aromatic complementarity. All columns feature advanced base material, optimized bonding, and proprietary surface treatments minimizing tailing. The company emphasizes selectivity optimization for difficult pharmaceutical separations. Stationary Phases: C18 Gravity, C18 Pyramid, C8, PFP, NH2, HILIC, Polar-RP, Phenyl Temperature: 5-45°C | 5-55°C (extended) Particle Sizes: 1.8µm, 3µm, 5µm, 10µm, 20µm Pore Size: 100Å, 120Å, 200Å Column Dimensions: Length 50-250mm | ID 2.0-10mm | Film Thickness 1.8-5.0µm Pressure: 400 bar | pH: 2-8 Key Features: Exceptional selectivity, Superior inertness, Excellent peak shape, High efficiency, Advanced silica chemistry, Low MS bleed, Thermal stability Detectors: UV, PDA, Fluorescence, RI, ELSD, MS, Corona CAD Applications: Difficult pharmaceutical separations, Impurity analysis, Complex mixtures, Environmental monitoring, Food safety, Method development, Fluorinated compound analysis